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Clinical Reviews

Acquired factor XI deficiency. A case report


Ortiz Palacios Ma, Iglesias Gómez Cb, Pelegrín López Bc, Castellar Reche MAd

aServicio de Pediatría. Hospital Clínico Universitario Virgen de la Arrixaca. Murcia, España.
bPediatra. CS Alcantarilla-Sangonera. Murcia. España.
cPediatra. CS Alcantarilla-Sangonera. Alcantarilla, Murcia. España.
dPediatra. CS Alcantarilla-Casco. Alcantarilla, Murcia. España.

Reference of this article.:

Ortiz Palacios M, Iglesias Gómez C, Pelegrín López B, Castellar Reche MA. Déficit de factor XI. A propósito de un caso. Rev Pediatr Aten Primaria. 2019;21:e205-e207.

Published in Internet: 10/10/2019


Factor XI deficiency is a hereditary coagulation disorder with a quantitative and/or qualitative reduction of factor XI due to F11 gene mutations. This is a common entity in Ashkenazi community, which can be underestimated in Caucasians. It can debut at any age with variable and unpredictable symptoms, showing poor relation between factor XI activity levels and bleeding symptoms. It can be diagnosed after a basic coagulation exam (lengthening activated partial thromboplastin time [APTT]) and factor XI levels measure. We present a factor XI deficiency clinical case for spreading this entity to the pediatric community.

Keywords: Haemophilia. Factor XI deficiency. Vaginal bleeding.



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